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Combating Periodontitis

With Locally Administered Antibiotics

Learning Objectives: 

After watching this animation, the listener should:

  • Understand the baseline causes of periodontal disease, and know why diligent management is important to long-term oral health
  • Know how locally administered antimicrobials (LAA) such as minocycline HCl operate to eliminate periodontal disease-causing bacteria

Millions of adult Americans suffer from progressive periodontitis.  Periodontitis is a disease believed to be caused by the accumulation of harmful bacteria (known as red-complex bacteria) in and around periodontal pockets.  Scaling and root planing (SRP) or "periodontal debridement" are the standard means of controlling periodontal disease, however these methods may not be enough to eliminate bacterial colonies that can return to baseline levels quickly after the procedures are performed.  When indicated, it is suggested that periodontal treatment involving SRP be used in conjunction with locally administered antimicrobials, which have been shown to increase pocket depth reduction and reduce the number of harmful bacteria in periodontal pockets for up to 14 days.

Related Reading: 

  1. http://thenextdds.com/Articles/Adjunctive-Therapy-to-Periodontal-Debridement/
  2. http://thenextdds.com/Articles/Management-of-Periodontal-Inflammations/
  3. http://thenextdds.com/Blogs/Periodontitis/Periodontitis---Intro-and-Treatment/
  4. Williams R, Paquette D, Offenbacher S, et al. Treatment of periodontitis by local administration of minocycline microspheres: A controlled trial. J Periodontol 2001;72(11):1535-1544.
  5. Meinberg T, Barnes C, Dunning D, Reinhardt R. Comparison of conventional periodontal maintenance versus scaling and root planing with subgingival minocycline. J Periodontol 2002;73(2):167-172.
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