Combating Periodontitis
With Locally Administered Antibiotics
THE NEXT DDS
Learning Objectives:
After watching this animation, the listener should:
- Understand
the baseline causes of periodontal disease, and know why diligent management is important to long-term oral health
- Know
how locally administered antimicrobials (LAA) such as minocycline HCl operate
to eliminate periodontal disease-causing bacteria
Millions of adult Americans suffer from progressive
periodontitis. Periodontitis is a disease believed to be caused by the accumulation
of harmful bacteria (known as red-complex bacteria) in and around periodontal
pockets. Scaling and root planing (SRP) or "periodontal debridement" are the standard means of controlling
periodontal disease, however these methods may not be enough to eliminate
bacterial colonies that can return to baseline levels quickly after the
procedures are performed. When indicated, it is suggested that periodontal treatment involving SRP be used in conjunction with locally
administered antimicrobials, which have been shown to increase pocket depth
reduction and reduce the number of harmful bacteria in periodontal pockets for
up to 14 days.
Related Reading:
- http://thenextdds.com/Articles/Adjunctive-Therapy-to-Periodontal-Debridement/
- http://thenextdds.com/Articles/Management-of-Periodontal-Inflammations/
- http://thenextdds.com/Blogs/Periodontitis/Periodontitis---Intro-and-Treatment/
- Williams
R, Paquette D, Offenbacher S, et al. Treatment of periodontitis by
local administration of minocycline microspheres: A controlled trial. J
Periodontol 2001;72(11):1535-1544.
- Meinberg
T, Barnes C, Dunning D, Reinhardt R. Comparison of conventional
periodontal maintenance versus scaling and root planing with subgingival
minocycline. J Periodontol 2002;73(2):167-172.