Periodontal Disease and the Role of Locally Administered Antimicrobials
THE NEXT DDS
After hearing this audio clip, the listener should:
the base line causes of periodontal disease, and know why it is such a
difficult disease to treat
how locally administered antimicrobials (LAA) such as minocycline operate
to eliminate periodontal disease causing bacteria
Millions of adult Americans suffer from progressive
periodontitis. Periodontitis is a disease which is caused by the accumulation
of harmful bacteria (known as red-complex bacteria) in and around periodontal
pockets. Scaling and root planing are the standard means of controlling
periodontal disease, however these methods may not be enough to eliminate
bacterial colonies which can return to baseline levels quickly after the
procedures are performed. When indicated, it is suggested that a treatment
planning involving scaling and root planing be used in conjunction with locally
administered antimicrobials, which have been shown to increase pocket depth
reduction and reduce the number of harmful bacteria in periodontal pockets for
up to 14 days.
R, Paquette D, Offenbacher S, et al. Treatment
of Periodontitis by Local Administration of Minocycline Microspheres: A
Controlled Trial. J Periodontol. 2001; Vol72(11): 1535-1544.
T, Barnes C, Dunning D, Reinhardt R. Comparison
of Conventional Periodontal Maintenance Versus Scaling and Root Planing
with Subgingival Minocycline. J Periodontol. 2002; Vol73(2): 167-172.